Bioactive Small Molecules
A vast array of small, non-peptide, organic compounds that are biologically active. Products include receptor antagonists, molecular probes, metabolites, GPCR ligands, neurotransmitters, ion channel modulators, and signaling activators and inhibitors.
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2,941
Tocris Bioscience™ C16
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PKR inhibitor
| CAS | 608512-97-6 |
|---|---|
| Product Type | Bioactive Small Molecule |
| Solubility | Soluble to 50mM in DMSO and to 20mM in ethanol |
| Purity | >98% |
| Physical Form | Solid |
| Chemical Name or Material | C16 |
| Recommended Storage | Store at -20°C |
| Synonym | 6,8-Dihydro-8-(1H-imidazol-5-ylmethylene)-7H-pyrrolo[2,3-g]benzothiazol-7-one |
| Molecular Formula | C13H8N4OS |
| Formula Weight | 268.29 |
2,942
Tocris Bioscience™ NSC 636819
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KDM4A/KDM4B inhibitor
| Target | Histone Demethylase Inhibitors |
|---|---|
| CAS | 1618672-71-1 |
| Purity | >98% |
| Chemical Name or Material | 1,5-Bis[(1E)-2-(3,4-dichlorophenyl)ethenyl]-2,4-dinitrobenzene |
| Recommended Storage | Store at 4°C |
| Molecular Formula | C22H12Cl4N2O4 |
| Formula Weight | 510.15 |
2,943
Tocris Bioscience™ DFHBI
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Mimic of GFP fluorophore for imaging RNA in living cells
| Target | Light-up Aptamers |
|---|---|
| CAS | 1241390-29-3 |
| Purity | >98% |
| Chemical Name or Material | (5Z)-5-[(3,5-Difluoro-4-hydroxyphenyl)methylene]-3,5-dihydro-2,3-dimethyl-4H-imidazol-4-one |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C12H10F2N2O2 |
| Formula Weight | 252.22 |
2,944
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Tocris Bioscience™ ZE 132
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Tocris Bioscience™ ZE 132
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Potent and selective PD-1/PD-L1 interaction inhibitor
2,945
Tocris Bioscience™ D 4476
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CAS: 301836-43-1 Molecular Formula: C23H18N4O3
| CAS | 301836-43-1 |
|---|---|
| Molecular Formula | C23H18N4O3 |
2,946
Tocris Bioscience™ AZD 5438
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CAS: 602306-29-6 Molecular Formula: C18H21N5O2S
| CAS | 602306-29-6 |
|---|---|
| Molecular Formula | C18H21N5O2S |
2,947
Tocris Bioscience™ TCS 359
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CAS: 301305-73-7 Molecular Formula: C18H20N2O4S
| CAS | 301305-73-7 |
|---|---|
| Molecular Formula | C18H20N2O4S |
2,948
Tocris Bioscience™ PH 797804
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Potent and selective p38α/β inhibitor
| Target | p38 Inhibitors |
|---|---|
| CAS | 1358027-80-1 |
| Purity | >98% |
| Chemical Name or Material | (-)-3-[3-Bromo-4-[(2,4-difluorophenyl)methoxy]-6-methyl-2-oxo-1(2H)-pyridinyl]-N,4-dimethylbenzamide |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C22H19BrF2N2O3 |
| Formula Weight | 477.3 |
2,949
Tocris Bioscience™ Ro 60-0175 fumarate
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CAS: 169675-09-6 Molecular Formula: C15H16ClFN2O4
| CAS | 169675-09-6 |
|---|---|
| Molecular Formula | C15H16ClFN2O4 |
2,950
Tocris Bioscience™ RS 246204
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R-Spondin-1 substitute used to initiate small intestinal organoids
| Target | Compounds for Stem Cell Proliferation & Renewal |
|---|---|
| Recommended Storage | Store at -20°C |
2,951
Tocris Bioscience™ 4-P-PDOT
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CAS: 134865-74-0 Molecular Formula: C19H21NO
| CAS | 134865-74-0 |
|---|---|
| Molecular Formula | C19H21NO |
2,952
Tocris Bioscience™ L-trans-2,4-PDC
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CAS: 64769-66-0 Molecular Formula: C6H9NO4
| CAS | 64769-66-0 |
|---|---|
| Molecular Formula | C6H9NO4 |
2,953
Tocris Bioscience™ PF 04628935
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Potent ghrelin receptor inverse agonist
| CAS | 1383719-97-8 |
|---|---|
| Chemical Name or Material | 1-[2-[[2-Chloro-4-(2H-1,2,3-triazol-2-yl)phenyl]methyl]-2,7-diazaspiro[3.5]non-7-yl]-2-(2-methylimidazo[2,1-b]thiazol-6-yl)ethanone |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C24H26ClN7OS |
| Formula Weight | Observed MW: 496.03 |
| Assay Percent Range | >98% |
2,954
Tocris Bioscience™ KH 7
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CAS: 330676-02-3 Molecular Formula: C17H15BrN4O2S
| CAS | 330676-02-3 |
|---|---|
| Molecular Formula | C17H15BrN4O2S |
2,955
Tocris Bioscience™ QO 58
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Kv7 channel opener
| Target | Voltage-gated Potassium Channel Activators |
|---|---|
| CAS | 1259536-62-3 |
| Purity | >98% |
| Chemical Name or Material | 5-(2,6-Dichloro-5-fluoro-3-pyridinyl)-3-phenyl-2-(trifluoromethyl)-pyrazolo[1,5-a]pyrimidin-7(4H)-one |
| Recommended Storage | Store at 4°C |
| Molecular Formula | C18H8Cl2F4N4O |
| Formula Weight | 443.18 |